MICROELECTRODE STUDY OF SPREADING DEPRESSION (SD) IN FROG RETINA
نویسندگان
چکیده
منابع مشابه
Spreading depression of activity in amphibian retina.
GOURAS, PETER. Spreading depression of activity in amphibian retina. Am. J. Physiol. 195(1): 28-32. [email protected] studies on excised amphibian retina have uncovered a phenomenon of spreading retinal depression which in many respects resembles Leao’s spreading cortical depression. The phenomenon is characterized by a spontaneous ‘milky’ wave that periodically marches across the surface of t...
متن کاملSpiral waves of spreading depression in the isolated chicken retina.
Existence of the theoretically predicted spiral waves of excitation in intact two-dimensional networks of excitable elements has been experimentally confirmed in the isolated chicken retina. The preparation supports the waves of Leão's spreading depression (SD) the concentric propagation of which from the point of origin can be directly observed as a change of the optical properties of the reti...
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Spreading depression (SD) and the related hypoxic SD-like depolarization (HSD) are characterized by rapid and nearly complete depolarization of a sizable population of brain cells with massive redistribution of ions between intracellular and extracellular compartments, that evolves as a regenerative, "all-or-none" type process, and propagates slowly as a wave in brain tissue. This article revie...
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Spreading depression (SD), a slow diffusion-mediated self-sustained wave of depolarization that severely disrupts neuronal function, has been implicated as a cause of cellular injury in a number of central nervous system pathologies, including blind spots in the retina. Here we show that in the hypoglycemic chicken retina, spontaneous episodes of SD can occur, resulting in irreversible punctate...
متن کاملThe effects of carbon dioxide, oxygen and pH on spreading depression in the isolated chick retina.
In the isolated chick retina, the propagation velocity of Spreading Depression (SD) was approximately doubled and the frequency of spontaneous waves was substantially increased with solutions bubbled with 5% CO2 instead of air, at constant pH (7.5-7.6). There was no effect on SD of raised pO2. Large changes of pH (to 6.4 and 9.4) produced, respectively, decreases and increases of velocity; but ...
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ژورنال
عنوان ژورنال: The Japanese Journal of Physiology
سال: 1976
ISSN: 1881-1396,0021-521X
DOI: 10.2170/jjphysiol.26.219